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KMID : 0359720230410020121
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Journal of the Korean Neurological Association
2023 Volume.41 No. 2 p.121 ~ p.127
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Decision-making Approach in Late-onset Bilateral Semantic Variant Primary Progressive Aphasia with Coexisting Asymmetric Regional Amyloid Deposition
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Oh Ki-Chang
Park Jeong-Ju
Yung Young-Bok
KIm Bo-Young
Kim Ji-Eun
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Abstract
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Semantic variant primary progressive aphasia (svPPA), a well-known subtype of the frontotemporal dementia often shows peculiar clinical features and structural neuroimage findings. To strengthen the accuracy of a clinical diagnosis, amyloid positron emission tomography-computed tomography (PET-CT) might be helpful. However, in patients with late-onset svPPA, an admixture of the various neuropathology would interfere with diagnostic approach. Herein, we report a case of late-onset bilateral svPPA showing a regional amyloid deposition on PET-CT scan.
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KEYWORD
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Semantics, Frontotemporal dementia, Amyloid
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